LoxP sites were inserted downstream of exon 5 and upstream of exon 15. An FRT-flanked neo cassette was removed by flp-mediated recombination. (J:170077)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count