A Pcsk9 DNA construct with an H229A active site mutation was placed under the control of an Apoe promoter and a liver specific enhancer. mRNA expression was 40 fold higher than normal. (J:169834)
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A Pcsk9 DNA construct with an H229A active site mutation was placed under the control of an Apoe promoter and a liver specific enhancer. mRNA expression was 40 fold higher than normal. (J:169834)