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A minigene consisting of the Gnrh1 promoter driving expression of a codon-improved cre (icre) flanked by two estrogen receptor binding domains (Esr1*) was microinjected into fertilized pronuclei to generate transgenic animals. High and low expressing lines were produced. (J:78663)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
