A 4471 kb fragment of the mouse telomerase reverse transcriptase (Tert) gene was used to drive expression of GFP in the construct. The construct was electroporated into J1 ES cells that were screened and selected for GFP expression. Transgenic mice were generated by standard methods from ES cells showing transgene expression. Lines 14 and 22 were analyzed extensively and demonstrated similar GFP expression patterns. Detailed analysis for line 22 was presented. (J:139017, J:169663)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae
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Insertion
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7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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