This allele was derived from Grem1tm1Ecan by deletion of a frt -flanked selection cassette that, followed by a loxP site, replaced the non-conserved final 66 bp of the 3'-UTR. The present allele contains a loxP site 335 bp upstream of the coding region-encompassing second exon and, within exon 2, the remaining frt site and second loxP site 550 bp downstream of the termination codon. (J:169133)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x C57BL/6)F1
Targeted
Insertion, Intragenic deletion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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