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Using GENSAT BAC engineering system, the Cre recombinase gene was introduced upstream of the ATG start codon of the gene of interest on a selected BAC clone. The inserted gene has its own ATG start codon and polyadenylation signal. This modification results in the expression of Cre recombinase that is under the control of the promoter and regulatory elements of the gene of interest that are present on the BAC clone. The BAC address for this line is RP23-278G4. SNP analysis has shown the transgenic insertion to be on chromosome 19 between SNPs rs3023496 and UT_4_59.889271. (J:100256)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
