An EGFP reporter gene, followed by a polyadenylation sequence, was inserted into BAC clone RP24-228M5 at the initiating ATG codon of the first coding exon of the Clu gene so that EGFP expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC (BX2353) was used to generate this transgene. (J:100256)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count