Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-6m17) containing the entire mouse zeta-chain (TCR) associated protein kinase (Zap70) gene. A point mutation was introduced in exon 8, resulting in the substitution of a methionine for an alanine (M413A). (J:167326)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6;129X1-Zap70tm1Weis/AnuApb
--
Insertion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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