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A construct consisting of the CMV beta-actin enhancer/promoter, a floxed PGK-EM7-neo-tPA cassette, a myc tagged Rheb cDNA containing an S16H mutation, and an SV40 poly(A) signal, was inserted via homologous recombination. Expression of the Rheb cDNA is silenced prior to cre mediated recombination. (J:168571)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
