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A targeting construct was designed to insert an enhanced green fluorescent protein sequence (EGFP) sequence (preceded by sequence for linker peptide CKDPPVAT) and a loxP-flanked neomycin (neo) resistance sequence-STOP cassette in the 3' UTR. Subsequent cre-mediated recombination removed the floxed neo-STOP cassette. This allele expresses a chimeric protein with the EGFP peptide linked to the C-terminus of the endogenous peptide. (J:168822)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
