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A human BCL2 cDNA sequence under the regulatory control of a rat Pklr promoter was used for the transgene. Rat Pklr regulatory sequences were used to drive transgene expression in hepatocytes, enterocytes, and proximal tubular cells of the kidney. The Pklr region includes the promoter, exon 1, and part of exon 2. Expression of the transgene in intestine, pancreas, liver, and kidney was confirmed by Northern and Western blot analysis. (J:81129)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
