Log In|Sign Up
EN
This transgene contains the coding exons of the chicken lysozyme gene downstream of the mouse metallothionein I (Mt1) promoter. Mice of this transgenic line constitutively express very little hen egg lysozyme, exhibiting very low concentrations in serum (>5 ng/ml). However, zinc induction of the promoter (by supplementing the drinking water with zinc sulfate (25mM) for >= 5 days) raises the serum HEL concentration to ~200 ng/ml. (J:78308, J:127344)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
