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A cassette containing, a floxed IRES-neo/STOP cassette followed by an IRES and human GNAS with nucleotide substitutions that result in the amino acid subsitution of cysteine for arginine at position 201 (R201C), was inserted downstream of the coding sequence in exon 7. This mutation produces a constitutively active protein. (J:168378)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
