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A three base deletion of TTC at nucleotide positions 1130-1132 in exon 9 was created. This causes the deletion of phenylalanine at amino acid residue 377. At the same time, a floxed PGK neomycin selection cassette was inserted in intron 8 608 bp 5' of the TTC deletion. Founder mice were crossed to cre expressing mice in order to excise the selection cassette. (J:168526)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
