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An IRES-beta galactosidase and PGK-neomycin cassette was inserted in exon 7.1 at the aspartic acid position 262. Isoform Go1-alpha was disrupted while beta galactosidase was placed under the control of the Gnao1 promoter. Absence of the protein product from brain and pancreatic islets was confirmed immunologically. (J:168245)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
