An FRT flanked neomycin selection cassette was inserted upstream of exon 2 and exon 2 was flanked with loxP sites. Mice were then crossed to transgenic mice expressing flp recombinase to excise the neomycin selection cassette. (J:168248)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count