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An FRT flanked neomycin resistance cassette was inserted upstream of exon3 and exons 3 to 5 were flanked by loxP sites. The floxed exons were subsequently excised by crossing to Tg(EIIa-cre)C5379Lmgd mice. Absence of transcript was confirmed by RT-PCR and Northern blot analysis. Absence of full length protein was shown by Western blot analysis. (J:167848)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
