A floxed neo cassette was inserted upstream of exon 2, and a loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette leaving exon 2 floxed. (J:168434)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count