A loxP site was inserted upstream of 3' enhancer (E3' or Rr159), and a floxed neo cassette was inserted downstream of the E3'. An FRT site was inserted upstream of the downstream enhancer (Ed or Rr160), and an FRT-flanked puro cassette was inserted downstream of the Ed. Cre-mediated recombination removed the E3' and flp-mediated recombination removed the Ed. (J:167472)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Intergenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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