A short hairpin RNA directed against Taz was targeted into the Rosa26 locus. The shRNA sequence is under the regulation of the H1/tetO operator fusion promoter. Correct mRNA knock-down was confirmed in embryonic stem cells. (J:167527)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count