Log In|Sign Up
EN
The construct contained a cre recombinase cassette and bovine poly(A) sequence inserted in-frame downstream of the Hoxb8 ATG site. Fertilized early-stage C57BL/6 x DBA/2 oocytes were injected with the linearized construct, and four founders were obtained. Founders were mated to generated transgenic lines, two of which (1403 and 1404) exhibited the expected expression pattern on a gross scale at E9.5 and E11.5. Line 1403 carries a single copy of the transgene and was characterized in detail. (J:168059)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
