A loxP site was inserted upstream of exon 14, and a neo cassette flanked by two loxP sites was inserted downstream of exon 15. The loxP-flanked regions, including exons 14 and 15 and the neo cassette, were removed by transient Cre-recombinase induced recombination. (J:166948)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count