A loxP site was inserted upstream of exon 4, and an FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. The absence of protein expression was confirmed by western blot analysis on ventricular and atrial extracts. (J:167590)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count