A cre-polyA cassette was inserted by homologous recombination into 5' UTR of exon 1 of the Dkk3 gene contained in the BAC clone RP23-12M6. The purified fragment was injected into fertilized one-cell oocytes from B6C3F1 mice. Line D9 was characterized and used further. (J:125324)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F1
--
Insertion
--
--
--
19

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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