Using the MICER gene targeting system, 5'Hprt and 3'Hprt vectors containing exons from either side of the targeted region, single loxP sites, and a neomycin or puromycin drug selection cassette were used to flank the region. Cre-mediated recombination removed Eif2c3, Eif2c1, and Eif2c4. (J:101977)
Basic Information
Insertion, Intergenic deletion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count