Using the MICER gene targeting system, 5'Hprt and 3'Hprt vectors containing exons from either side of the targeted region, single loxP sites, and a neomycin or puromycin drug selection cassette were used to flank the region. Cre-mediated recombination removed Eif2c3, Eif2c1, and Eif2c4. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion, Intergenic deletion, Intragenic deletion
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--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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