A loxP site and a neo cassette flanked by two loxP sites were inserted to flank the last two exons (5 and 6). The neo cassette was removed in vivo by Cre-mediated recombination. (J:167124, J:194130)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count