Two loxP sites were inserted flanking the coding sequence of exon 9 which contains the whole ETS DNA binding and C-terminal domains. This was followed by an FRT flanked neomycin resistance cassette. The selection cassette was subsequenty excised by transient flp expression. Exon 9 was then excised in the germline by cre expression. (J:167426)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
Insertion, Intragenic deletion
--
1
7
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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