An ERT2 ligand binding domain was inserted upstream and in-frame of exon 1, and a floxed neo cassette was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette. (J:167227)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count