A gene trap cassette inserted into the first intron of the gene, and is predicted to truncate the encoded protein after lysine 32 (K31). The trap contains long terminal repeats (LTR), a splice acceptor (SA), a beta-Geo selective cassette containing beta-galactosidase and neo genes. A pair of FRT and loxP recombination signals in antisense orientation flanks the beta-Geo cassette. (J:219642)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count