Tow loxP sites were inserted to flank part of intron 1, exons 2-4 and the 3'UTR. An FRT site-flanked neomycin resistance gene was introduced followed by the second loxP site, and removed later by Flp-mediated recombination. A beta-galactosidase gene was also inserted after the second loxP site. Cre-mediated recombination of the loxP-flanked gene segment creates an in frame translation of beta-galactosidase. (J:167000)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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