These mice were created using MICER targeting vectors. Prmt2 was targeted using a vector selected from the 3' HPRT library and the Col6a1 locus in cis was targeted using a vector selected from the 5' HPRT library. Mice carrying this construct were crossed with Tg(CMV-cre)1Ipc transgenic mice. Cre expression results in excision of a 0.5 MB segment of chromosome 10 containing 13 genes, 9 withknown functions. (J:167506)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
Intergenic deletion, Intragenic deletion
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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