A FRT-flanked PGK-neo selection cassette resides downstream of the polyadenylation signal of the endogenous gene, and loxP sites are present 46 bp upstream of the ATG translation initiation codon and downstream of the neo cassette. The 3' loxP site is followed by the coding sequence for E. coli beta-galactosidase (lacZ) with a nuclear localization signal. (J:164344)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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