The Pax4-cre transgene was designed with the mouse paired box gene 4 (Pax4) promoter directing expression of an enhanced green fluorescent protein fused to a tet-off cassette (EGFP/tTA). The transgene also contained a tetracycline-responsive element witha CMV minimal promoter (tetO-CMVmin) driving expression of a cre-recombinase. (J:119944)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count