A loxP site was inserted upstream of exon 4 and a second loxP site followed by an FRT flanked hygromycin thymidine kinase cassette were inserted downstream of exon 14 via homologous recombination. Flp mediated recombination removed the hygromycin thymidine kinase cassette. (J:167157)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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