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The part of exon 2 encoding amino acids 1 through 346 was replaced with an FRT flanked DTR-EGFP cassette and a cre recombinase gene witha nuclear localization sequence. Subsequent flp mediated recombination removed the DTR-EGFP cassette and brought the cre recombinase under the control of the endogenous gene promoter. (J:167075, J:186624, J:207456)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
