Log In|Sign Up
EN
A loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette, a loxP site, a modified coding region containing nucleotide substitutions that result in the amino acid substitution of phenylalanine for serine at position 17 (S17F), and an IRES-EGFP were inserted downstream of the coding region. Flp-mediated recombination removed the neo cassette. Additional cre-mediated recombination is required to remove the endogenous coding region and allow for expression of the modified one. (J:166732)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
