This transgene contains the reverse tetracycline-regulated transactivator gene rtTA under control of the bovine keratin 5 promoter. The rtTA coding sequence lies downstream of approximately 5.2 kilobases of DNA from the 5' flanking region of the keratin followed by a beta-globin intron and upstream of an SV40 polyadenylation signal. Eleven lines were generated. The pound symbol (#) is used to denote when no line is psecified or multiple lines are pooled. (J:65791)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
--
--
60

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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