The loxP site inserted upstream of exon 2 was lost leaving a floxed neo cassette downstream of exon 3. The absence of protein expression was confirmed by western blot analysis. (J:167023)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count