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An 800 bp cassette composed of 3 copies of a 34 bp oligonucleotide containing the DR5 retinoic acid response element (RARE) upstream of the Hspa1b promoter was cloned into a plasmid ahead of the cre coding sequence. The construct was used to generate mice, with two founders demonstrating the expected cre mRNA in situ pattern being obtained. The founder displaying the highest expression level was used for further study. (J:166703)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
