The Afp::mCherry transgene was designed with a monomeric red fluorescent protein, mCherry, driven by alpha fetoprotein (Afp) promoter/enhancer sequences, followed by a rabbit beta-globin polyadenylation site. Line 1 was generated. Under control of Afp, mCherry labels the visceral endoderm and its derivatives, including the visceral yolk sac and gut endoderm. Expression is also seen in fetal liver and pancreas, and in liver, pancreas, digestive tract, and brain of postnatal mice. (J:166734)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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