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The AflII-XmaIII fragment of a human mineralocorticoid receptor cDNA (accession number NM_000901) from position 203 to 3198, including the full-length coding sequence, was blunt-ended and inserted into the EcoRV site located between the tetO promoter and the rabbit beta-globin polyadenylation sequence of the bidirectional tet-inducible pBI4 vector resulting in the tetO-hMR construct. Two founder lines were studied; in addition to line L1, line L2 was also produced. (J:112171)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
