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In ES cells containing F9tm1Dws, the neo cassette was replaced with sequence corresponding to the 5' Hprt minigene, exon 1, a modified exon 2, and exon 3. The modified exon 2 contains nucleotide substitutions that result in the amino acid substitution of alanine for lysine at position 5 (K5A). (J:166332)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
