A neomycin selection cassette was flanked by loxP sites and inserted in front of the EGFP sequence in a plasmid. The construct was injected into D3 ES cells and correctly targeted clones were injected into C57BL/6 blastocysts. (J:91302)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count