At the stop codon an additional BamHI was inserted as well as a C-terminal c-Myc epitope tag with a stop codon. A floxed puro cassette was inserted downstream of exon 12. Cre mediated recombination removed the puro cassette. (J:166151)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count