Log In|Sign Up
EN
In a BAC, a loxP site was inserted into exon 1 of Dlx1, 1345 bp upstream of the ATG site. The Venus reporter open reading frame was fused to the ATG, followed by a downstream loxP site, the SV40 polyA, and a removable selection cassette. The modifications were performed in a bacterial system by recombineering methods. The selection cassette was removed from the construct prior to injection into fertilized eggs. Cre-mediated recombination extinguishes Venus expression. Before recombination, reporter expression is detected in Dlx1-expressing cells. Founder line information was not available. (J:164291)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
