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The codon-improved cre sequence (icre) containing a nuclear localization signal was fused to the initiation codon of the Zic4 gene located in a BAC. The icre sequence was followed by the simian SV40 polyA signal and an Frt-flanked kanamycin selection cassette. The selection cassette was removed from the construct before injection inot fertilized eggs. Number of founder animals and line numbers are not available. (J:164291)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
