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A lox66 site was inserted upstream of exon 33. The following vector was inserted into intron 34 (5' through 3'): eGFP, exon 33 splice acceptor site, lox77 site, and FRT flanked neo cassette. Flp mediated recombination removed the neo cassette. Cre mediated recombination inverted the region between lox66 and lox77, bringing eGFP into frame after exon 32. The predicted product is truncated after the 17th calcium-binding epidermal growth factor-like domain (cbEGF17) and called GT8 ("green truncated" from founder mouse 8). (J:165897)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
