A septad of tetracycline response element with a minimal CMV promoter drive inducible expression of the mouse cDNA with nucleotide substitutions that result in the amino acid substitution of a stop codon for arginine at position 899 (R899X). The cDNA has a C-terminal FLAG tag and is followed by the beta-globin intron and polyadenylation sequence. The amino acid substitution does not alter SMAD activity. No line number or name was provided (designated by #). (J:142266)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count