A loxP site was inserted upstream of exon 4, an FRT site was inserted upstream of exon 4a, and a neo cassette flanked by attP and attB with 3' FRT and loxP site was inserted downstream of exon 4a. Flp mediated recombination removed the neo cassette and exon 4a. Exon 4 remains floxed. Real-time RT-PCR confirms the absence of the kidney specific transcript isoform. (J:165537)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
2
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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