The 510 bp rat elastase 1 enhancer/promoter (Cela1) was used to drive expression of a rat pancreatic secretory trypsin inhibitor minigene (Spink3) containing all four exons and 2 kb of 3' flanking DNA. The three entrons were all shortened for ease in handling. Two of the four founders identified were used to extablish lines of transgenic mice. (J:96743)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6SJLF1
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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